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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CHI-HF-211VSIG4-C100 | 100 µg | - | - |
3 - 9 business days* |
429.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
VSIG4 (V-set and immunoglobulin domain containing 4), as known as complement receptor of the... more
Product information "VSIG4 (human):Fc (mouse) (rec.)"
VSIG4 (V-set and immunoglobulin domain containing 4), as known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation.
Keywords: | CRIg, VSIG4, Protein Z39Ig, V-set and immunoglobulin domain-containing protein 4, V-set and immunoglobulin domain containing 4, Z39Ig, CRIg |
Supplier: | Chimerigen Laboratories |
Supplier-Nr: | HF-211VSIG4 |
Properties
Application: | Bioassays |
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | ~68 kD |
Purity: | >98% |
Format: | Lyophilized |
Database Information
KEGG ID : | K19822 | Matching products |
UniProt ID : | Q9Y279 | Matching products |
Gene ID | GeneID 11326 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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