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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-APrEST70141.100 | 100 µl | - | - |
7 - 10 business days* |
247.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors,... more
Product information "VAMP8 PrEST Antigen"
Protein function: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t- SNARE complex (PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets (PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes. Participates also in the activation of type I interferon antiviral response through a TRIM6-dependent mechanism (PubMed:31694946). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: | EDB, VAMP-8, Endobrevin, Vesicle-associated membrane protein 8 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | APrEST70141 |
Properties
Application: | Control antigen |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
Database Information
KEGG ID : | K08512 | Matching products |
UniProt ID : | Q9BV40 | Matching products |
Gene ID | GeneID 8673 | Matching products |
Handling & Safety
Storage: | -20°C (avoid repeat freezing and thawing cycles) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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