Transferrin, Human (Rhodamine), Highly Purified

Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 79.5kD and a serum concentration range of 1800-2700mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. Label: Tetramethylrhodamine isothiocyanate (TRITC) (Molecular Weight 444 daltons) , Absorption Wavelength: 550 nm , Emission Wavelength: 570 nm , Fluorochrome/Protein Ratio: 3.5 moles TRITC per mole of Human Transferrin