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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
375662.20 | 20 µg | - | - |
3 - 19 business days* |
511.00€
|
||
375662.100 | 100 µg | - | - |
3 - 19 business days* |
773.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of... more
Product information "TRADD, Recombinant, Human, aa1-312, GST-Tag (Tumor Necrosis Factor Receptor Type 1-associated Death"
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. Source: Recombinant protein corresponding to aa1-312 from human TRADD, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~61.2kD, AA Sequence: MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | TRADD, TNFRSF1A-associated via death domain, TNFR1-associated DEATH domain protein, Tumor necrosis factor receptor type 1-associated DEATH domain protein |
Supplier: | United States Biological |
Supplier-Nr: | 375662 |
Properties
Conjugate: | No |
MW: | 61,2 |
Format: | Highly Purified |
Database Information
KEGG ID : | K03171 | Matching products |
UniProt ID : | Q15628 | Matching products |
Gene ID | GeneID 8717 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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