Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay14073-100 | 100 µg | - |
6 - 10 business days* |
465.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Tudor domains are small protein structural motifs of ~50 amino acids related to the "royal... more
Product information "TP53BP1 tudor-like region (human recombinant)"
Tudor domains are small protein structural motifs of ~50 amino acids related to the "royal family" of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains. They are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. Tudor domains recognize symmetric methylated arginine or methylated lysine residues. TP53BP1 binds both histone and non-histone substrates. Binding of TP53BP1 to dimethylated lysine 382 on p53 (p53 K382me2), as well as histone H4K20me2, through the tudor domain, has been shown to be important for TP53BP1 localization to DNA double strand breaks. This product contains the tudor domain of TP53BP1.Synonyms: 53BP1, Tumor Suppressor p53-binding Protein 1. Purity: >90%. Source: Recombinant N-terminal GST-tagged protein expressed in E. coli. Amino Acids: 1717-1972 (N- and C-terminal truncations). MW: 42.6 kDa. Formulation: (Request formulation change), 50 mM Tris-HCl, pH 8.0, containing 150 mM sodium chloride and 20% glycerol. UniProt Accession #: Q12888.
Keywords: | 53BP1, 53BP1, p53BP1, p53BP1, p53-binding protein 1, p53-binding protein 1, TP53-binding protein 1, TP53-binding protein 1 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 14073 |
Properties
Application: | Methyl reader |
Conjugate: | No |
Host: | E.coli |
MW: | 42,6 kD |
Purity: | >90% |
Format: | Solution |
Database Information
KEGG ID : | K20915 | Matching products |
UniProt ID : | Q12888 | Matching products |
Gene ID | GeneID 7158 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed