TNFR1/TNFRSF1A protein (His tag), recombinant mouse

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Mouse Tnfrsf1a protein (P25118) (1-212) was expressed with a C-His . Sequence: Met1-Ala212. Fusion tag: C-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 35 kDa. Protein function: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. Ther Protein function: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. [The UniProt Consortium]