Thioredoxin Domain-Containing Protein 12/TXNDC12/ERp18 Protein(C-6His) (recombinant human)

Protein Construction: Recombinant Human Thioredoxin Domain-Containing Protein 12 is produced by our Mammalian expression system and the target gene encoding His27-Leu168 is expressed with a 6His tag at the C-terminus. Sequence: His27-Leu168. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 18 kDa. Protein function: Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. TXNDC12 is widely expressed in many tissues and contains one thioredoxin domain. Protein function: Possesses significant protein thiol-disulfide oxidase activity. [The UniProt Consortium]