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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-40T-0101-C050 | 50 µg | - |
3 - 9 business days* |
495.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Full-length TDO (Anopheles gambiae) is fused at the N-terminus to a His-tag. Liquid. In 50mM... more
Product information "TDO (Anopheles gambiae) (rec.) (His)"
Full-length TDO (Anopheles gambiae) is fused at the N-terminus to a His-tag. Liquid. In 50mM sodium phosphate pH 8.0, containing 0.15M sodium chloride, 0.2M imidazole and 10% glycerol. Tryptophan 2,3-dioxygenase (TDO) is a heme-containing dioxygenase catalyzing the addition of molecular oxygen across the 2,3-double bond of the indole ring of tryptophan to form N-formylkynurenine (NFK). In Anopheles gambiae, TDO is the only enzyme able to catalyze the first and rate-limiting step in L-Trp catabolism through the kynurenine pathway. Tryptophan is an essential amino acid for protein synthesis and also the precursor for production of a number of neurotransmitters, such as serotonin and melatonin, in mosquitoes, the kynurenine pathway is essential for eye pigmentation. Conceivably, the tryptophan-using pathways should be regulated in a coordinated manner in mosquitoes as well as in other species and TDO activation/inactivation processes could play an essential role in these phenomena.
Keywords: | TO, TDO, TRPO, AGAP002721, EC=1.13.11.11, Tryptophanase, Tryptophan pyrrolase, Tryptophan oxygenase, Tryptamin 2,3-dioxygenase, Tryptophan 2,3-dioxygenase |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-40T-0101 |
Properties
Application: | Enzyme assays |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | Anopheles gambiae |
MW: | 47.9 kD |
Format: | Liquid |
Database Information
KEGG ID : | K00453 | Matching products |
UniProt ID : | O77457 | Matching products |
Gene ID | GeneID 1273245 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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