SPSB2, Recombinant, Human, aa1-263, His-Tag (SPRY Domain-containing SOCS Box Protein 2, GRCC9, SSB2)

SPSB2 is a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. This protein is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Source: Recombinant protein corresponding to aa1-263 from human SPSB2 at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~31.2kD (287aa), AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSH ERRPVAQSTD GARGKRGYSR GLHAWEISWP LEQRGTHAVV GVATALAPLQ TDHYAALLGS NSESWGWDIG RGKLYHQSKG PGAPQYPAGT MGQTAL AGGSSSTPTP QALYPDLSCP EGLEELLSAP PPDLGAQRRH GWNPKDCSEN IEVKEGGLYF, QGEQLEVPER LLVVLDMEEG TLGYAIGGTY LGPAFRGLKG RTLYPAVSAV WGQCQVRIRY LGERRAEPHS LLHLSRLCVR HNLGDTRLGQ VSALPLPPAM KRYLLYQ, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.