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SMYD2 protein-GST fusion

Rockland
SMYD2 protein-GST fusion
Item number Size Datasheet Manual SDS Delivery time Quantity Price
009-001-T43S 20 µg - -

6 - 10 business days*

468.00€
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Description Product Citations Certificate of Analysis Reviews 0
Description
Recombinant full-length human SMYD2 was expressed by baculovirus in Sf9 insect cells using an... more
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Product information "SMYD2 protein-GST fusion"
Recombinant full-length human SMYD2 was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >85% by densitometry. Protein function: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. [The UniProt Consortium]
Keywords: SMYD2, KMT3C, HSKM-B, EC=2.1.1.-, EC=2.1.1.43, Lysine N-methyltransferase 3C, Histone methyltransferase SMYD2, N-lysine methyltransferase SMYD2, SET and MYND domain-containing protein 2
Supplier: Rockland Immunochemicals
Supplier-Nr: 009-001-T43S

Properties

Application: WB
Conjugate: No
Host: Human

Database Information

KEGG ID : K11426 | Matching products
UniProt ID : Q9NRG4 | Matching products
Gene ID GeneID 56950 | Matching products

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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