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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-APrEST73240.100 | 100 µl | - | - |
7 - 10 business days* |
247.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Transporter that mediates the import of reduced folates and a subset of cyclic... more
Product information "SLC19A1 PrEST Antigen"
Protein function: Transporter that mediates the import of reduced folates and a subset of cyclic dinucleotides (PubMed:7826387, PubMed:9041240, PubMed:10787414, PubMed:15337749, PubMed:16115875, PubMed:31126740, PubMed:31511694). Has high affinity for N5-methyltetrahydrofolate, the predominant circulating form of folate (PubMed:10787414, PubMed:14609557, PubMed:22554803). Also able to mediate the import of antifolate drug methotrexate (PubMed:7615551, PubMed:7641195, PubMed:9767079, PubMed:22554803). Acts as an importer of immunoreactive cyclic dinucleotides, such as cyclic GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response to DNA virus in the cytosol, and its linkage isomer 3'-3'-cGAMP (PubMed:31126740, PubMed:31511694). Mechanistically, acts as an antiporter, which export of intracellular organic anions to facilitate uptake of its substrates (PubMed:22554803, PubMed:31126740, PubMed:31511694). 5-amino-4-imidazolecarboxamide riboside (AICAR), when phosphorylated to AICAR monophosphate, can serve as an organic anion for antiporter activity (PubMed:22554803). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
| Keywords: | RFC, hRFC, FOLT, IFC-1, FLOT1, RFT-1, hSLC19A1, Reduced folate transporter, Intestinal folate carrier 1, Placental folate transporter, Reduced folate transporter 1, Reduced folate carrier protein |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | APrEST73240 |
Properties
| Application: | Control antigen |
| Conjugate: | No |
| Host: | E.coli |
| Species reactivity: | human |
Database Information
| KEGG ID : | K14609 | Matching products |
| UniProt ID : | P41440 | Matching products |
| Gene ID | GeneID 6573 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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