SIN3A PrEST Antigen

SIN3A PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST87485.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1... more
Product information "SIN3A PrEST Antigen"
Protein function: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. Required for cortical neuron differentiation and callosal axon elongation. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: Transcriptional corepressor Sin3a, Paired amphipathic helix protein Sin3a, Histone deacetylase complex subunit Sin3a
Supplier: Atlas Antibodies
Supplier-Nr: APrEST87485

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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