Shc, Recombinant, Human, aa1-474, His-tag (SHC1, Src homology and collagen, Src homology 2, FLJ26504

Shc, Recombinant, Human, aa1-474, His-tag (SHC1, Src homology and collagen, Src homology 2, FLJ26504
Item number Size Datasheet Manual SDS Delivery time Quantity Price
S1010-91G.100 100 µg - -

1 - 19 business days

451.00€
 
SHC1 (SHC-transforming protein 1) belongs to the SH2 domain family. SHC1 has been found to be... more
Product information "Shc, Recombinant, Human, aa1-474, His-tag (SHC1, Src homology and collagen, Src homology 2, FLJ26504"
SHC1 (SHC-transforming protein 1) belongs to the SH2 domain family. SHC1 has been found to be important in the regulation of apoptosis and drug resistance in mammalian cells. It is a signaling adapter that couples activated growth factor receptors to signaling pathway. SHC1 expressed in neural stem cells but absent in mature neurons. Purified by using conventional chromatography techniques. Source: Recombinant corresponding to aa1-474 of human SHC1, fused to His-tag at N-terminal, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MNKLSGGGGR RTRVEGGQLG GEEWTRHGSF VNKPTRGWLH PNDKVMGPGV SYLVRYMGCV EVLQSMRALD FNTRTQVTRE AISLVCEAVP GAKGATRRRK PCSRPLSSIL GRSNLKFAGM PITLTVSTSS LNLMAADCKQ IIANHHMQSI SFASGGDPDT , AEYVAYVAKD PVNQRACHIL ECPEGLAQDV ISTIGQAFEL RFKQYLRNPP KLVTPHDRMA GFDGSAWDEE EEEPPDHQYY NDFPGKEPPL GGVVDMRLRE GAAPGAARPT APNAQTPSHL GATLPVGQPV GGDPEVRKQM PPPPPCPAGR ELFDDPSYVN VQNLDKARQA VGGAGPPNPA , INGSAPRDLF DMKPFEDALR VPPPPQSVSM AEQLRGEPWF HGKLSRREAE ALLQLNGDFL VRESTTTPGQ YVLTGLQSGQ PKHLLLVDPE GVVRTKDHRF ESVSHLISYH MDNHLPIISA GSELCLQQPV ERKL, Molecular Weight: ~53.8kD (494aa) , Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: SHC-transforming protein 3, SHC-transforming protein 1, SHC-transforming protein A, Src homology 2 domain-containing-transforming protein C1
Supplier: United States Biological
Supplier-Nr: S1010-91G

Properties

Conjugate: No
MW: 53,8 kD
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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