SARS-CoV-2 (2019-nCoV) Papain-Like Protease Protein , recombinant

SARS-CoV-2 (2019-nCoV) Papain-Like Protease Protein , recombinant
COVID-19 Research
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-PKSR030472.10 10 µg - -

7 - 16 business days*

240.00€
E-PKSR030472.50 50 µg - -

7 - 16 business days*

633.00€
 
GenBank: QHD43415.1. Nsp3 is responsible for the cleavages located at the N-terminus of the... more
Product information "SARS-CoV-2 (2019-nCoV) Papain-Like Protease Protein , recombinant"
GenBank: QHD43415.1. Nsp3 is responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling. [The Uniprot Consortium]
Keywords: Non-structural protein 3, nsp3, PL2-PROPapain-like proteinase, PL-PRO, SARS coronavirus main proteinase
Supplier: Elabscience
Supplier-Nr: PKSR030472

Properties

Conjugate: No
Expressed in: E.coli
Origin: Sars-cov-2
MW: 34 kD
Purity: > 90 % as determined by reducing SDS-PAGE.
Format: Solution

Database Information

UniProt ID : P0DTD1 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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