S100 Calcium Binding Protein A7, Recombinant, Human, aa1-101, His-tag (S100A7, S100A7c, HGNC:10497,

S100A7, also known as Psoriasin, belongs to the S-100 family of calcium binding proteins and is secreted via a non-classical secretory pathway into the cytoplasm. It is thought to function in the regulation of many cellular processes, including the cell cycle, cell progression and cellular differentiation. It contains two EF-hand domains and is highly upregulated in psoriatic epidermis, as well as in bladder squamous cell carcinoma and breast cancer tissue, suggesting a possible role in carcinogenesis. Source: Recombinant corresponding to aa1-101 from human S100A7, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSNTQAERSI IGMIDMFHKY TRRDDKIDKP SLLTMMKENFPNFLSACDKK GTNYLADVFE KKDKNEDKKI DFSEFLSLLG DIATDYHKQS HGAAPCSGGS Q , Molecular Weight: ~13.6kD (121aa), confirmed by MALDI-TOF, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.