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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay10765-250 | 250 µg | - |
6 - 10 business days* |
481.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Retinoblastoma protein-interacting zinc finger protein 1 (RIZ1), also known as PRDM2, is a... more
Product information "RIZ1 (human recombinant)"
Retinoblastoma protein-interacting zinc finger protein 1 (RIZ1), also known as PRDM2, is a SAM-dependent histone methyltransferase that specifically methylates histone H3 on lysine 9. RIZ1 contains 8 zinc-finger motifs and 1 PR domain. The RIZ gene encodes two different proteins, RIZ1 and RIZ2. RIZ1 is a tumor suppressor that can arrest the cell cycle and induce apoptosis. RIZ2 however, is a proto-oncoprotein lacking the N-terminal PR domain containing the methyltransferase activity. When RIZ1 is silenced or mutated, the reduced methyltransferase activity can lead to inheritable changes in chromatin methylation and gene expression patterns.Synonyms: KMT8, PRDM2, PR Domain Zinc Finger Protein 2, Retinoblastoma Protein-interacting Zinc Finger Protein. Purity: >85% estimated by SDS-PAGE. Source: recombinant N-terminal GST-tagged protein expressed in E. coli. Amino Acids: 2-200 (C-terminal truncation). MW: 49.5 kDa. UniProt Accession #: Q13029.
| Keywords: | KMT8, PRDM2, MTB-ZF, MTB-ZF, MTE-binding protein, MTE-binding protein, Zinc finger protein RIZ, Zinc finger protein RIZ, GATA-3-binding protein G3B, GATA-3-binding protein G3B, Lysine N-methyltransferase 8, Lysine N-methyltransferase 8, PR domain-containi |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 10765 |
Properties
| Application: | Methylation studies |
| Conjugate: | No |
| Host: | E.coli |
| MW: | 49,5 kD |
| Purity: | >85% estimated by SDS-PAGE |
Database Information
| KEGG ID : | K11432 | Matching products |
| UniProt ID : | Q13029 | Matching products |
| Gene ID | GeneID 7799 | Matching products |
Handling & Safety
| Storage: | -80°C |
| Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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