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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| DC-715-H16-0BU | 100 µg | - | - |
3 - 8 business days* |
519.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: [Spike protein S1]: attaches the virion to the cell membrane by interacting... more
Product information "Recombinant SARS-CoV-2 Spike Glycoprotein S1 RBD (HEK)"
Protein function: [Spike protein S1]: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32075877, PubMed:32155444). Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651). Can be alternatively processed by host furin (PubMed:32362314). Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes. [The UniProt Consortium]
| Keywords: | 2 |
| Supplier: | Diaclone |
| Supplier-Nr: | 715-H16-0BU |
Properties
| Conjugate: | No |
| Host: | Human cells |
| Species reactivity: | SARS-CoV-2 |
Database Information
| KEGG ID : | K24152 | Matching products |
| UniProt ID : | P0DTC2 | Matching products |
| Gene ID | GeneID 43740568 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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