Recombinant Rabbit Tumor Necrosis Factor a/TNF-a

Recombinant Rabbit Tumor Necrosis Factor a/TNF-a
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-32-7070-10 10 µg - -

3 - 11 business days*

418.00€
ABE-32-7070-50 50 µg - -

3 - 11 business days*

713.00€
 
Source: E.coli. MW :17.59kD. Recombinant Rabbit Tumor Necrosis Factor alpha is produced by our... more
Product information "Recombinant Rabbit Tumor Necrosis Factor a/TNF-a"
Source: E.coli. MW :17.59kD. Recombinant Rabbit Tumor Necrosis Factor alpha is produced by our E.coli expression system and the target gene encoding Val77-Leu235 is expressed. Tumor necrosis factor alpha (TNFa) is the prototypic ligand of the TNF superfamily. TNFa forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFa is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFa is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. [The UniProt Consortium]
Supplier: Abeomics
Supplier-Nr: 32-7070

Properties

Conjugate: No

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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