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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-RPES3178.20 | 20 µg | - | - | - |
9 - 20 business days* |
1,015.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Mouse IL6RA/CD126 Recombinant Protein (RPES3178) is a highly pure recombinant protein developed... more
Product information "Recombinant Mouse IL6RA/CD126 Protein (His Tag) (RPES3178)"
Mouse IL6RA/CD126 Recombinant Protein (RPES3178) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications Protein function: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling', the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells. [The UniProt Consortium]
Keywords: | Il6r |
Supplier: | Assay Genie |
Supplier-Nr: | RPES3178 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | mouse |
Format: | Highly Purified |
Database Information
KEGG ID : | K05055 | Matching products |
UniProt ID : | P22272 | Matching products |
Gene ID | GeneID 16194 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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