Recombinant Human SMYD2/KMT3C Protein (His Tag) (RPES3621)

Recombinant Human SMYD2/KMT3C Protein (His Tag) (RPES3621)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPES3621.20 20 µg - - -

9 - 20 business days*

1,015.00€
 
Human SMYD2/KMT3C Recombinant Protein (RPES3621) is a highly pure recombinant protein developed... more
Product information "Recombinant Human SMYD2/KMT3C Protein (His Tag) (RPES3621)"
Human SMYD2/KMT3C Recombinant Protein (RPES3621) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications Protein function: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. [The UniProt Consortium]
Keywords: KMT3C, SMYD2, HSKM-B, Lysine N-methyltransferase 3C, Histone methyltransferase SMYD2, N-lysine methyltransferase SMYD2, SET and MYND domain-containing protein 2
Supplier: Assay Genie
Supplier-Nr: RPES3621

Properties

Conjugate: No
Host: Insect cells
Species reactivity: human
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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