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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| E-PKSH031669.100 | 100 µg | - |
7 - 16 business days* |
539.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9... more
Product information "Recombinant Human SMAC / Diablo Protein (His tag)"
Protein function: Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 attenuates the stability and apoptosis- inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway. Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation. Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance. [The UniProt Consortium]
| Supplier: | Elabscience |
| Supplier-Nr: | E-PKSH031669 |
Properties
| Conjugate: | No |
| Species reactivity: | human |
| Format: | Lyophilized |
Database Information
| KEGG ID : | K10522 | Matching products |
| UniProt ID : | Q9NR28 | Matching products |
| Gene ID | GeneID 56616 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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