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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-32-9053-50 | 50 µg | - | - |
3 - 11 business days* |
978.00€
|
||
ABE-32-9053-500 | 500 µg | - | - |
3 - 11 business days* |
2,618.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Source : Human Cells,Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and... more
Product information "Recombinant Human Collagen a-1(VIII) Chain/COL8A1 (C-6His)"
Source : Human Cells,Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. COL8A1 forms homotrimers or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrahedron stabilized by central interacting C-terminal NC1 trimers. COL8A1 is mainly expressed in the subendothelium of large blood vessels. The expression level can be up-regulated during vascular injury, in atherosclerosis and in diabetes. COL8A1 is necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis. Protein function: Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis. [The UniProt Consortium]
Supplier: | Abeomics |
Supplier-Nr: | 32-9053 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
Database Information
KEGG ID : | K23455 | Matching products |
UniProt ID : | P27658 | Matching products |
Gene ID | GeneID 1295 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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