Recombinant Human Collagen a-1(IX) Chain/COL9A1 (C-6His)

Source: Human Cells. MW :33.8kD. Recombinant Human COL9A1 is produced by our Mammalian expression system and the target gene encoding Ala24-Pro328 is expressed with a 6His tag at the C-terminus. COL9A1, which is short for Collagen alpha-1(IX) chain, is a 921 aa. protein. It is a secreted protein, and exists in extracellular space and extracellular matrix. This protein is a heterotrimer of an alpha 1(IX), an alpha 2(IX) and an alpha 3(IX) chain.Each subunit is composed of three triple-helical domains interspersed with non-collagenous domains. The globular domain at the N-terminus of type IX collagen molecules represents the NC4 domain which may participate in electrostatic interactions with polyanionic glycosaminoglycans in cartilage. It ia a structural component of hyaline cartilage and vitreous of the eye. Protein function: Structural component of hyaline cartilage and vitreous of the eye. [The UniProt Consortium]