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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
374993.20 | 20 µg | - | - |
3 - 19 business days* |
575.00€
|
||
374993.100 | 100 µg | - | - |
3 - 19 business days* |
855.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A... more
Product information "RASSF5, Recombinant, Human, aa1-265, GST-Tag (Ras Association Domain-containing Protein 5)"
Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis. Source: Recombinant protein corresponding to aa1-265 from human RASSF5, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~57.4kD, AA Sequence: MTVDSSMSSGYCSLDEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | RAPL, NORE1, RASSF5, New ras effector 1, Ras association domain-containing protein 5, Regulator for cell adhesion and polarization enriched in lymphoid tissues |
Supplier: | United States Biological |
Supplier-Nr: | 374993 |
Properties
Conjugate: | No |
MW: | 57,4 |
Format: | Highly Purified |
Database Information
KEGG ID : | K08015 | Matching products |
UniProt ID : | Q8WWW0 | Matching products |
Gene ID | GeneID 83593 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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