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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
R1200-10G.100 | 100 µg | - | - |
3 - 19 business days* |
500.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
RAS viral (r-ras) oncogene homolog 2 isoform a, also known as RRAS2, belongs to the Ras like... more
Product information "Ras R2, Recombinant Human (RAS viral (r-ras) oncogene homolog 2, RRAS2)"
RAS viral (r-ras) oncogene homolog 2 isoform a, also known as RRAS2, belongs to the Ras like GTPase family that cycle between GTP-bound active and GDP-bound inactive states at the cytoplasmic face of the plasma membrane. It is implicated in the pathogenesis of human cancers. Thus, overexpression of active RRAS2 in EpH4 cells induces tumorigenicity through the phosphoinositide 3-kinase, p38 MAPK, and mTOR pathways, and these cells lose their sensitivity to the normal growth inhibitory role of TGF-beta. Recombinant human RRAS2, fused to His-tag at N-terminus, , expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant corresponding to human RRAS2, aa1- 201, his-tagged, expressed in E. coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAAAGWRDGS GQEKYRLVVV GGGGVGKSAL TIQFIQSYFV TDYDPTIEDS YTKQCVIDDR AARLDILDTA GQEEFGAMRE QYMRTGEGFL LVFSVTDRGS FEEIYKFQRQ ILRVKDRDEF PMILIGNKAD LDHQRQVTQE EGQQLARQLK VTYMEASAKI, RMNVDQAFHE LVRVIRKFQE QECPPSPEPT RKEKDKKGCH C, Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.
Keywords: | TC21, RRAS2, Ras-like protein TC21, Teratocarcinoma oncogene, Ras-related protein R-Ras2 |
Supplier: | United States Biological |
Supplier-Nr: | R1200-10G |
Properties
Conjugate: | No |
Species reactivity: | human |
Format: | Affinity Purified |
Database Information
KEGG ID : | K07830 | Matching products |
UniProt ID : | P62070 | Matching products |
Gene ID | GeneID 22800 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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