RANK:Fc, Recombinant, Human (TRANCE-R, TNFRSF11A, ODFR, Osteoclast Differentiation Factor Receptor,

RANK (TRANCE-R, CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells. Human RANK (aa 29-213) is fused at the C-terminus to the Fc portion of human IgG1. , Biological Activity:, Inhibits human rhsRANKL biological functions. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.