RAD54L PrEST Antigen

RAD54L PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST71056.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: Plays an essential role in homologous recombination (HR) which is a major... more
Product information "RAD54L PrEST Antigen"
Protein function: Plays an essential role in homologous recombination (HR) which is a major pathway for repairing DNA double-strand breaks (DSBs), single-stranded DNA (ssDNA) gaps, and stalled or collapsed replication forks (PubMed:9774452, PubMed:24798879, PubMed:32457312, PubMed:11459989, PubMed:12205100, PubMed:27264870). Acts as a molecular motor during the homology search and guides RAD51 ssDNA along a donor dsDNA thereby changing the homology search from the diffusion-based mechanism to a motor-guided mechanism. Plays also an essential role in RAD51-mediated synaptic complex formation which consists of three strands encased in a protein filament formed once homology is recognized. Once DNA strand exchange occured, dissociates RAD51 from nucleoprotein filaments formed on dsDNA. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: hHR54, RAD54A, RAD54L, hRAD54, RAD54 homolog, DNA repair and recombination protein RAD54-like
Supplier: Atlas Antibodies
Supplier-Nr: APrEST71056

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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