PIGR/SC protein (His tag), recombinant human

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Human PIGR/SC protein (P01833) (Lys 19-Ala 561) was expressed with a N-His tag. Sequence: Lys 19-Ala 561. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 59 kDa. Protein function: Polymeric immunoglobulin receptor, also known asPIGR, is a member of the immunoglobulin superfamilyand aFc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a tran Protein function: [Polymeric immunoglobulin receptor]: Mediates selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells. Binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. [The UniProt Consortium]