Periostin (mouse, rec.)

(3 x 10µg). Mouse Periostin (amino acids 24-783) is fused at the C-terminus to a FLAG(R)-tag. Lyophilized. Contains PBS. Periostin was originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta1 (TGFbeta1) and bone morphogenetic protein (BMP2). Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.