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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-40T-0013-C010 | 10 µg | - |
3 - 9 business days* |
319.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Human full-length PARP-3 [ARTD3] is fused to a HA-tag and a His-tag. Liquid. In 50mM TRIS-HCl, pH... more
Product information "PARP-3 [ARTD3] (human) (rec.) (His) (high purity)"
Human full-length PARP-3 [ARTD3] is fused to a HA-tag and a His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. PARP-3 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Keywords: | IRT1, ARTD3, PARP3, ADPRT3, PARP-3, hPARP-3, ADPRT-3, pADPRT-3, EC=2.4.2.30, Poly[ADP-ribose] synthase 3, Poly [ADP-ribose] polymerase 3, NAD(+) ADP-ribosyltransferase 3, ADP-ribosyltransferase diphtheria toxin-like 3 |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-40T-0013 |
Properties
Application: | Enzyme assays |
Conjugate: | No |
Host: | Insect cells |
Species reactivity: | human |
Format: | Liquid |
Database Information
KEGG ID : | K10798 | Matching products |
UniProt ID : | Q9Y6F1 | Matching products |
Gene ID | GeneID 10039 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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