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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-APrEST75899.100 | 100 µl | - | - |
7 - 10 business days* |
247.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated... more
Product information "NPLOC4 PrEST Antigen"
Protein function: The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I (PubMed:26471729). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
| Keywords: | NPLOC4, KIAA1499, Protein NPL4, Nuclear protein localization protein 4 homolog |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | APrEST75899 |
Properties
| Application: | Control antigen |
| Conjugate: | No |
| Host: | E.coli |
| Species reactivity: | human |
Database Information
| KEGG ID : | K14015 | Matching products |
| UniProt ID : | Q8TAT6 | Matching products |
| Gene ID | GeneID 55666 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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