Mouse CD178 / Fas Ligand recombinant protein (Active) (His-tagged)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG70401.20	20 µg		-	-	6 - 14 business days*		360.00€
ARG70401.100	100 µg		-	-	6 - 14 business days*		900.00€

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Protein function: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic... more

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Product information "Mouse CD178 / Fas Ligand recombinant protein (Active) (His-tagged)"

Protein function: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:26334989, PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:9228058, PubMed:7528780, PubMed:9427603). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen- activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (PubMed:27806260). {ECO:0000250, UniProtKB:P41047, ECO:0000269, PubMed:17557115, ECO:0000269, PubMed:27806260, ECO:0000269, PubMed:7528780, ECO:0000269, PubMed:9228058, ECO:0000269, PubMed:9427603}. [The UniProt Consortium]

Keywords:	APL, SPA, APTL, FasL, FASLG, CD178, sFasL, CD95-L, APT1LG1, FasL ICD, Fas ligand, CD95 ligand, Fas antigen ligand, Soluble Fas ligand, Apoptosis antigen ligand, FasL intracellular domain, ADAM10-processed FasL form, SPPL2A-processed FasL form, Receptor-bi
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG70401

Properties

Application:	SDS-PAGE
Conjugate:	No
Species reactivity:	mouse
Format:	Purified

Database Information

KEGG ID :	K04389 \| Matching products
UniProt ID :	P48023 \| Matching products
Gene ID	GeneID 356 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	-20°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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