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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay40876-100 | 100 µg | - | - |
6 - 10 business days* |
600.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Middle East respiratory syndrome coronavirus (MERS-CoV) spike glycoprotein is a viral structural... more
Product information "MERS-CoV Spike Glycoprotein RBD (Strain EMC/2012) (recombinant)"
Middle East respiratory syndrome coronavirus (MERS-CoV) spike glycoprotein is a viral structural protein that contains the receptor-binding domain (RBD). MERS-CoV is an enveloped positive-stranded RNA virus, a member of the Betacoronavirus genus, and the causative agent of MERS, an acute respiratory disease that often leads to pneumonia and renal failure. The MERS-CoV spike glycoprotein mediates viral attachment to host cells and virus-cell-mediated membrane fusion during infection. It is composed of an S1 subunit, which contains the RBD that binds to host dipeptidyl peptidase-4 (DPP-4), and an S2 subunit containing heptad repeat regions 1 and 2, which are responsible for membrane fusion, as well as a transmembrane domain and a cytoplasmic tail. The RBD of the MERS-CoV spike glycoprotein is one of the targets for neutralizing antibodies. Cayman's MERS-CoV Spike Glycoprotein RBD (Strain EMC/2012) (recombinant) protein consists of 251 amino acids and has a calculated molecular weight of 27.7 kDa.Synonyms: MERS-CoV Spike Glycoprotein Receptor-Binding Domain, Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein RBD, Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein Receptor-Binding Domain. Purity: >90% as estimated by SDS-PAGE. Endotoxin Testing: <1.0 EU/µg determined by the LAL endotoxin assay. Source: Recombinant MERS-CoV C-terminal His-tagged spike glycoprotein RBD expressed in insect cells. Amino Acids: 367-606. MW: 27.7 kDa. Formulation: (Request formulation change), Lyophilized from sterile 20 mM Tris, 500 mM sodium chloride, 10% glycerol, pH 8.0. UniProt Accession #: K0BRG7.
Keywords: | E2, S glycoprotein, Peplomer protein, Spike protein S1, Spike protein S2, Spike protein S2', Spike glycoprotein |
Supplier: | Cayman Chemical |
Supplier-Nr: | 40876 |
Properties
Conjugate: | No |
Host: | Insect cells |
Species reactivity: | MERS-CoV |
Purity: | >90% as estimated by SDS-PAGE |
Format: | Lyophilized |
Database Information
UniProt ID : | K0BRG7 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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