MADD PrEST Antigen

MADD PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST80537.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: Plays a significant role in regulating cell proliferation, survival and death... more
Product information "MADD PrEST Antigen"
Protein function: Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Isoform 5 shows increased cell proliferation and isoform 2 shows decreased. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis), isoform 1 is susceptible to inducing apoptosis, isoform 5 is resistant and isoform 3 and isoform 4 have no effect. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: Rab3 GDP/GTP exchange factor, Insulinoma glucagonoma clone 20, MAP kinase-activating death domain protein, Differentially expressed in normal and neoplastic cells
Supplier: Atlas Antibodies
Supplier-Nr: APrEST80537

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Database Information

UniProt ID : Q8WXG6 | Matching products
Gene ID GeneID 8567 | Matching products

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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