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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSM041105.10 | 10 µg | - |
7 - 16 business days* |
139.00€
|
|||
E-PKSM041105.50 | 50 µg | - |
7 - 16 business days* |
352.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: Recombinant Mouse Lymphotoxin beta Receptor is produced by our Mammalian... more
Product information "Lymphotoxin ß Receptor/LTBR/TNFRSF3/TNFRrp Protein(C-Fc) (recombinant mouse)"
Protein Construction: Recombinant Mouse Lymphotoxin beta Receptor is produced by our Mammalian expression system and the target gene encoding Ser28-Pro218 is expressed with a Fc tag at the C-terminus. Sequence: Ser28-Pro218. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 61kDa. Protein function: It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs. The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of the encoded protein can trigger apoptosis. Not only does the TNFRSF3 help trigger apoptosis, it can lead to the release of the cytokine interleukin 8. Overexpression of TNFRSF3 in Human Cells cells increases IL-8 promoter activity and leads to IL-8 release. TNFRSF3 is also essential for development and organization of the secondary lymphoid organs and chemokine release. Protein function: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. [The UniProt Consortium]
Keywords: | Ltbr, Tnfcr, Lymphotoxin-beta receptor, Tumor necrosis factor receptor superfamily member 3, Recombinant Mouse Lymphotoxin ß Receptor/LTBR/TNFRSF3/TNFRrp Protein(C-Fc) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSM041105 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | mouse |
MW: | 48.7 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K03159 | Matching products |
UniProt ID : | P50284 | Matching products |
Gene ID | GeneID 17000 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | +4°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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