Latexin, Recombinant, Human, aa1-222

Latexin, a carboxypeptidase A inhibitor, is highly expressed in heart, prostate, ovary, kidney, pancrease, and colon, moderaqte or low in other tissues including brain. Latexin has no detectable sequence similarity with plant and parasite inhibitors, but it is related to a human putative tumor suppressor protein, TIG1. It is down-regulated in the presenilin-1-deficient mouse brain, thus putatively playing a role in Alzheimer's disease. Source: Recombinant protein corresponding to aa1-222 of human Latexin expressed in E. coli. Molecular Weight: ~25.7kD, Endotoxin: ~1EU/1ug of protein (LAL) , AA Sequence:, MEIPPTNYPA SRAALVAQNY INYQQGTPHR VFEVQKVKQA SMEDIPGRGH KYRLKFAVEE IIQKQVKVNC TAEVLYPSTG QETAPEVNFT FEGETGKNPD EEDNTFYQRL KSMKEPLEAQ NIPDNFGNVS PEMTLVLHLA WVACGYIIWQ NSTEDTWYKM VKIQTVKQVQ RNDDFIELDY TILLHNIASQ EIIPWQMQVL WHPQYGTKVK HNSRLPKEVQ LE, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.