LAMP3/CD208/DC-LAMP Protein (His Tag), recombinant rat

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Rat LAMP3 (Q5XI99-1) (Tyr21-Thr373) was expressed with a polyhistidine tag at the N-terminus. Sequence: Tyr21-Thr373. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 40.84 kDa. Protein function: Might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells. Protein function: Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity. [The UniProt Consortium]