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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay11237-100 | 100 µg | - | - |
6 - 10 business days* |
642.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Methylation of lysine residues in core histones plays a critical role in regulating gene... more
Product information "JMJD2E Strep-tagged (human, recombinant)"
Methylation of lysine residues in core histones plays a critical role in regulating gene expression. Jumonji domain containing 2E (JMJD2E) catalyzes the demethylation of histone H3 at lysince residue 9. Like other JmjC protein hydroxylase family members, JMJD2E is an alpha-ketoglutarate-dependent Fe (II) oxygenase. Purification of Fe-dependent JmjC family members by IMAC can result in displacement of the catalytic iron and decreased activity, therefore this Strep-tagged protein is purified by affinity chromatography using Strep-Tactin coated resin. Because of their implication in cancer cell growth, jumonji C domain-containing histone demethylase inhibitors may have the capacity to be anticancer agents.Synonyms: Jumonji Domain Containing 2E, KDM4D-Like. Purity: >75% estimated by SDS-PAGE. Source: active recombinant N-terminal Strep II-tagged protein expressed in E. coli. Amino Acids: 2-337. MW: 40.8 kDa. Formulation: (Request formulation change), 20 mM HEPES, pH 7.4, and 150 mM sodium chloride. License: Sold under license from IBA.. UniProt Accession #: B2RXH2.
Keywords: | KDM4E, KDM4DL, KDM4D-like protein, KDM4D-like protein, Lysine-specific demethylase 4E, Lysine-specific demethylase 4E, Lysine-specific demethylase 4D-like, Lysine-specific demethylase 4D-like, [histone H3]-trimethyl-L-lysine(9) demethylase 4E, [histone H3 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 11237 |
Properties
Application: | Enzyme activity |
Conjugate: | No |
Host: | E.coli |
MW: | 40,8 kD |
Purity: | >75% estimated by SDS-PAGE |
Format: | Solution |
Database Information
KEGG ID : | K06709 | Matching products |
UniProt ID : | B2RXH2 | Matching products |
Gene ID | GeneID 390245 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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