Hormone-Sensitive Lipase (human, recombinant)

Hormone-sensitive lipase (HSL) is a key enzyme regulating the mobilization of fatty acids from intracellular stores. There are three different isoforms of the enzyme: HSLadi, which is the predominant form found in adipocytes, HSLtes expressed in testes, and HSLb found in insulin secreting beta-cells. The three isoforms are distinguished by their molecular masses. HSL catalyses the rate limiting step in the lipolysis of triacylglycerol, found in intracellular stores, to fatty acids. HSL also catalyzes the hydrolysis of mono- and diacylglycerides, as well as cholesterol esters.Synonyms: HSL, LIPE. Source: Active recombinant N-terminal His-tagged protein, expressed in Sf21 insect cells using a baculovirus expression system. Amino Acids: 2-1,076 (full-length). MW: 118.3 kDa. UniProt Accession #: Q05469.