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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay11080-500 | 500 µg | - |
6 - 10 business days* |
642.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Histone H2A type 1 (H2A.1) is a variant of the histone H2A protein that is encoded by H2AC11,... more
Product information "Histone H2A Type 1 (human, recombinant)"
Histone H2A type 1 (H2A.1) is a variant of the histone H2A protein that is encoded by H2AC11, previously known as HIST1H2AG, in humans. Histone H2A is a core histone that forms a dimer with histone H2B. Two histone H2A/H2B dimers form an octameric nucleosome with a histone H3/H4 tetramer, around which DNA wraps, allowing it to be condensed. Histone H2A can be post-translationally modified via methylation of the arginine at position 3 by protein arginine methyltransferase 1 (PRMT1), PRMT5, or PRMT6, which is associated with both transcriptional activation and repression. When methylated by PRMT7, it is associated with DNA damage repair. The arginine residue at position 3 of histone H2A is also subject to citrullination by protein arginine deiminase 4 (PAD4). H2A.1 levels are higher in peripheral blood mononuclear cells (PBMCs) isolated from patients with active systemic lupus erythematosus (SLE) compared to those with stable SLE, rheumatoid arthritis (RA), or non-SLE non-RA controls. Cayman's Histone H2A Type 1 (human, recombinant) protein can be used for Western blot and ELISA applications.Synonyms: H2A Clustered Histone 11, H2A Histone Family, Member P, H2A.1, H2AC11, H2AFP, HIST1H2AG, Histone H2A/ptl. Purity: >90% estimated by SDS-PAGE. Source: Recombinant human histone H2A type 1 expressed in E. coli. Amino Acids: 2-130 (full length). MW: 13.96 kDa. Formulation: (Request formulation change), A solution in water. UniProt Accession #: P0C0S8.
Keywords: | H2AFP, H2AFC, H2AFD, H2AFI, H2AFN, H2A.1, H2A.1, Histone H2A/ptl, Histone H2A/ptl, Histone H2A type 1, Histone H2A type 1 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 11080 |
Properties
Application: | WB |
Conjugate: | No |
Host: | E.coli |
MW: | 13.96 kD |
Purity: | >90% estimated by SDS-PAGE |
Format: | Solution |
Database Information
KEGG ID : | K11251 | Matching products |
UniProt ID : | P0C0S8 | Matching products |
Gene ID | GeneID 8329 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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