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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay39629-50 | 50 µg | - | - |
6 - 10 business days* |
530.00€
|
||
Cay39629-100 | 100 µg | - | - |
6 - 10 business days* |
953.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Glutathione peroxidase 1 (GPX1) is a selenocysteine-containing glutathione peroxidase with... more
Product information "GPX1 (human, recombinant)"
Glutathione peroxidase 1 (GPX1) is a selenocysteine-containing glutathione peroxidase with antioxidant activity. It is ubiquitously expressed and localizes to both the cytosol and mitochondria. GPX1 catalyzes the reduction of hydrogen peroxide, hydroperoxy fatty acids, and hydroperoxy lysophosphatides to water or their corresponding non-toxic lipid alcohols, respectively, by converting glutathione (GSH) to oxidized glutathione (GSSG), thereby reducing intracellular oxidative stress. GPX1 levels are increased in renal cell carcinoma tumors compared with non-tumor renal tissue and correlated with decreased overall patient survival. Plasma levels of GPX1 are decreased in asthmatic patients and GPX1 SNPs are associated with an increased risk of the development of asthma. Cardiac GPX1 levels and whole blood GPX1 activity are decreased in patients with Keshan disease, an endemic cardiomyopathy associated with low selenium levels in the soil and food supply. Cayman's GPX1 (human, recombinant) protein can be used for enzyme activity assays.Synonyms: Glutathione Peroxidase 1, GPXD, GSHPX1. Purity: >95% estimated by SDS-PAGE. Source: Active recombinant human GPX1 expressed in E. coli. Amino Acids: 203 residues. Formulation: (Request formulation change), 25 mM Tris-HCl, pH 8.0, with 250 mM potassium chloride, 2 mM 2-mercaptoethanol, and 10% glycerol.
Keywords: | GPx-1, GSHPx-1, Glutathione peroxidase 1, Cellular glutathione peroxidase, GPXD, GSHPX1 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 39629 |
Properties
Application: | Active enzyme |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
Purity: | >95% estimated by SDS-PAGE |
Format: | Solution |
Database Information
KEGG ID : | K00432 | Matching products |
UniProt ID : | P07203 | Matching products |
Gene ID | GeneID 2876 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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