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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH033927.10 | 10 µg | - |
7 - 16 business days* |
234.00€
|
|||
E-PKSH033927.50 | 50 µg | - |
7 - 16 business days* |
699.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: Recombinant Human Glycosylphosphatidylinositol-anchored High Density... more
Product information "GPIHBP1 (C-Fc) (recombinant human)"
Protein Construction: Recombinant Human Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 is produced by our Mammalian expression system and the target gene encoding Thr22-Gly151 is expressed with a Fc tag at the C-terminus. Sequence: Thr22-Gly151. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 50-65 kDa. Protein function: Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) is a member of the Ly6 family of proteins, binds LPL in the subendothelial spaces and transports it to the capillary lumen. GPIHBP1 is an important regulator of triglyceride metabolism by increasing the efficiency of lydrolysis by LPL and uptake of fatty acids. GPIHBP1 was positively correlated with LPL, and GPIHBP1 is a better marker for body weight decrease than LPL. Protein function: Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries. Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries. Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding (PubMed:27929370, PubMed:29899144). Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis (PubMed:19304573, PubMed:21314738). Binds chylomicrons and phospholipid particles that contain APOA5 (PubMed:17997385, PubMed:19304573). Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL. [The UniProt Consortium]
Keywords: | HBP1, GPIHBP1, GPI-HBP1, GPI-anchored HDL-binding protein 1, High density lipoprotein-binding protein 1, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, Recombinant Human GPIHBP1 (C-Fc) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH033927 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | 41.7 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K20001 | Matching products |
UniProt ID : | Q8IV16 | Matching products |
Gene ID | GeneID 338328 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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