GP, Recombinant, Zaire Ebolavirus, aa33-364, His-SUMO-Tag (Pre-Small/Secreted Glycoprotein)

sGP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not se to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils. Delta-peptide does not seem to be involved in activation of primary macrophages. Source: Recombinant protein corresponding to aa33-364 from zaire ebolavirus Pre-Small/Secreted Glycoprotein, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~53.3kD, AA Sequence: IPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKTSLEKFAVKSCLSQLYQTEPKTSVVRVRRELLPTQGPTQQLKTTKSWLQKIPLQWFKCTVKEGKLQCRI, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.