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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH030582.100 | 100 µg | - |
7 - 16 business days* |
1,016.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: A DNA sequence encoding the mature foem of human GNGT1 (P63211) (Pro 2-Cys... more
Product information "GNGT1 / GNG1 Protein (His tag) (recombinant human)"
Protein Construction: A DNA sequence encoding the mature foem of human GNGT1 (P63211) (Pro 2-Cys 71) was expressed, with a polyhistide tag at the N-terminus. Sequence: Pro 2-Cys 71. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 9.0 kDa. Protein function: GNGT1 is a subunit of of transducin. Heterotrimeric G proteins consist of alpha, beta, and gamma subunits. They are membrane bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-transmembrane-helix G protein-coupled receptors. They are involved as a modulator or transducer in various transmembrane signaling systems. G proteins are bound to GDP in the 'off' state. GNGT1 is the gamma subunit of transducin. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins, in addition, some Gbetagamma subunits have active functions. Gbetagamma coupled to H1 receptors can activate PLA2 and Gbetagamma coupled to M1 receptors can activate KIR channels. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. [The UniProt Consortium]
Keywords: | GNGT1, Transducin gamma chain, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Recombinant Human GNGT1 / GNG1 Protein (His tag) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH030582 |
Properties
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
MW: | 9.9 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K04548 | Matching products |
UniProt ID : | P63211 | Matching products |
Gene ID | GeneID 2792 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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