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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay10755-50 | 50 µg | - | - |
6 - 10 business days* |
530.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Post-translational modification of histones by methylation of lysine residues can promote... more
Product information "G9a-like protein (human recombinant)"
Post-translational modification of histones by methylation of lysine residues can promote transcriptional activation or repression. G9a-like protein (GLP) and G9a are SET domain-containing methyltransferases that specifically mono- and di-methylate histone H3 at lysine 9 (H3K9). Methylation of H3K9 by a GLP/G9a heteromeric complex regulates gene expression by silencing euchromatin. GLP and G9a share 80% sequence identity in their SET domains. Structure-activity relationship (SAR) studies have been employed to design potent and selective inhibitors of these proteins, including BIX-01294 and UNC0638, with IC50 values in the nanomolar range.Synonyms: EHMT1, Euchromatic Histone-Lysine N-Methyltransferase 1, Eu HMTase 1, GLP, KMT1D. Purity: >95% estimated by SDS-PAGE. Source: active recombinant N-terminal GST-tagged protein expressed in E. coli. MW: 60.3 kDa. UniProt Accession #: Q9H9B1.
Keywords: | GLP, GLP, GLP1, GLP1, EHMT1, EUHMTASE1, Eu-HMTase1, Eu-HMTase1, H3-K9-HMTase 5, H3-K9-HMTase 5, G9a-like protein 1, G9a-like protein 1, Lysine N-methyltransferase 1D, Lysine N-methyltransferase 1D, Histone H3-K9 methyltransferase 5, Histone H3-K9 methyltr |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10755 |
Properties
Application: | Enzyme activity |
Conjugate: | No |
Host: | E.coli |
MW: | 60,3 kD |
Purity: | >95% estimated by SDS-PAGE |
Database Information
KEGG ID : | K11420 | Matching products |
UniProt ID : | Q9H9B1 | Matching products |
Gene ID | GeneID 79813 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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