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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH030547.100 | 100 µg | - |
7 - 16 business days* |
1,016.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: A DNA sequence encoding the human FAM20B (NP_055679.1)(Ser31-Leu409) was... more
Product information "FAM20B / Gxk1 Protein (Fc tag) (recombinant human)"
Protein Construction: A DNA sequence encoding the human FAM20B (NP_055679.1)(Ser31-Leu409) was expressed with the fused Fc region of human IgG1 at the N-terminus. Sequence: Ser31-Leu409. Fusion tag: N-Fc Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method. Apparent Molecular Mass: 72.2 kDa. Protein function: PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins which are produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived from the placenta. Pregnancy specific glycoproteins (PSGs) are the most abundant placentally derived glycoproteins in the maternal serum. PSG1, PSG6, PSG6N, and PSG11 induce dose-dependent secretion of anti-inflammatory cytokines by human monocytes. Human and murine PSGs exhibit cross-species activity. Protein function: Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG- protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1- O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-phosphorylation may influence the catalytic activity of B3GAT3 (GlcAT-I) which completes the precursor tetrasaccharide of GAG-protein linkage regions on which the repeating disaccharide region is synthesized. [The UniProt Consortium]
Keywords: | Xylose kinase, Glycosaminoglycan xylosylkinase, Recombinant Human FAM20B / Gxk1 Protein (Fc tag) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH030547 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | 71.4 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K20825 | Matching products |
UniProt ID : | O75063 | Matching products |
Gene ID | GeneID 9917 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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