ENO1, Human

Sequence: SILKIHAREI FDSRGNPTVE VDLFTSKGLF RAAVPSGAST GIYEALELRD NDKTRYMGKG VSKAVEHINK TIAPALVSKK LNVTEQEKID DGTENKSKFG ANAILGVSLA VCKAGAVEKG VPLYRHIADL AGNSEVILPV PAFNVINGGS HAGNKLAMQE FMILPVGAAN FREAMRIGAE HNLKNVIKEK YGKDATNVGD EGGFAPNILE NKEGLELLKT AIGKAGYTDK VVIGMDVAAS EFFRSGKYDL DFKSPDDPSR YISPDQLADL IKDYPVVSIE DPFDQDDWGA WQKFTASAGI QVVGDDLTVT NPKRIAKAVN EKSCNCLLLK VNQIGSVTES LQACKLAQAN SGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAKwith polyhistidine tag at the N-terminus Endotoxin level: <0.1 EU per 1 µg of the protein by the LAL method. Protein function: Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (PubMed:29775581, PubMed:1369209). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses (PubMed:2005901, PubMed:10802057, PubMed:12666133, PubMed:29775581). May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (PubMed:12666133). Stimulates immunoglobulin production (PubMed:1369209). [The UniProt Consortium]