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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E8949-34C.50 | 50 µg | - | - |
3 - 19 business days* |
606.00€
|
||
E8949-34C.250 | 250 µg | - | - |
3 - 19 business days* |
1,288.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
EIF3J (Eukaryotic translation initiation factor 3 subunit J) belongs to the EIF-3 subunit J... more
Product information "EIF3S1, Recombinant, Human, aa70-258, His-tag (Eukaryotic Translation Initiation Factor 3 Subunit J,"
EIF3J (Eukaryotic translation initiation factor 3 subunit J) belongs to the EIF-3 subunit J family. EIF3 plays a central role in binding of initiator methionyl-tRNA and mRNA to the 40S ribosomal subunit to form the 40S initiation complex. EIF3J binds to the aminoacyl (A) site and mRNA entry channel of the 40S subunit, placing EIF3J directly in the ribosomal decoding center. EIF3J also interacts with eIF1A and reduces 40S subunit affinity for mRNA. A high affinity for mRNA is restored upon recruitment of initiator tRNA, even though EIF3J remains in the mRNA-binding cleft in the presence of tRNA. Source: Recombinant corresponding to aa70-258 from human EIF3J, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MKISEKKKIA EKIKEKERQQ KKRQEEIKKR LEEPEEPKVL TPEEQLADKL RLKKLQEESD LELAKETFGV NNAVYGIDAM NPSSRDDFTE FGKLLKDKIT QYEKSLYYAS FLEVLVRDVC ISLEIDDLKK ITNSLTVLCS EKQKQEKQSK AKKKKKGVVP GGGLKATMKD DLADYGGYDG GYVQDYEDFM, Molecular Weight: ~24kD (MALDI-TOF), Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | EIF3J, eIF3j, EIF3S1, PRO0391, eIF3 p35, eIF-3-alpha, Eukaryotic translation initiation factor 3 subunit 1, Eukaryotic translation initiation factor 3 subunit J |
Supplier: | United States Biological |
Supplier-Nr: | E8949-34C |
Properties
Conjugate: | No |
Species reactivity: | human |
Format: | Highly Purified |
Database Information
KEGG ID : | K03245 | Matching products |
UniProt ID : | O75822 | Matching products |
Gene ID | GeneID 8669 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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