E2F2 protein (His tag), recombinant human

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Human E2F2 protein (Q14209) (Ala 65-Asn 437) was expressed with a N-His tag. Sequence: Ala 65-Asn 437. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 55 kDa. Protein function: E2F-2 (viral E2-associated factor 2) is a 50-55 kDa member of the E2F/DP family of transcription factors. It is principally expressed by placenta, and forms a DNA-activating E2F heterodimeric complex with DP-1 or -2. This complex, when active, promotes ce Protein function: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner. [The UniProt Consortium]