DNAJC15, Recombinant, Human, aa58-150, His-Tag (DnaJ homolog subfamily C member )

DNAJC15 contains 1 J domain. This protein is expressed ubiquitously and located on the membrane. DNAJC15 is absent or down-regulated in many advanced cases of ovarian adenocarcinoma, due to hypermethylation and allelic loss. Loss of expression correlates with increased resistance to antineoplastic drugs, such as cisplatin. Source: Recombinant protein corresponding to aa58-150 of human DNAJC15, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~12.8kD, AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSFRIWKPL EQVITETAKK ISTPSFSSYY KGGFEQKMSR REAGLILGVS PSAGKAKIRT AHRRVMILNH PDKGGSPYVA AKINEAKDLL ETTTKH, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.